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Vignettes

DNA genotyping & copy number analysis

  • CRMA (v1): Total copy number analysis using CRMA v1 (10K, 100K, 500K)
  • CRMA (v1&v2): Paired total copy number analysis
  • CRMA (v2): Estimation of total copy numbers using the CRMA v2 method (10K-GWS6)
  • CRMA (v1&v2): Sex-chromosome bias-corrected reference signals from pooled average
  • Total Copy Number Analysis (5.0 & 6.0) [DEPRECATED]
  • Calculating raw total copy numbers manually
  • MSCN: Multi-source copy-number normalization
  • MSCN: Creating binary data files containing copy number estimates
  • ACNE: Allele-specific copy numbers using non-negative matrix factorization [TO BE ADDED]
  • TumorBoost - Normalization of allelic-specific copy numbers in tumors with matched normals
  • TumorBoost - Normalization of allelic-specific copy numbers in tumors with matched normals (low-level API)

RNA expression analysis

  • RMA: Gene 1.0 ST array analysis
  • FIRMA: Human exon array analysis
  • FIRMA: Using the GenomeGraphs package with FIRMA

Tiling array analysis

  • MAT: (Promoter 1.0R) Tiling array analysis

Miscellaneous

  • Empirical probe-signal densities and rank-based quantile normalization
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